A study has been conducted on the Indus delta to evaluate the environmental degradation and spatially geomorphic change occurred over the region in last three to four decades. Based on the results, it has been identified that i) the coastline is rapidly receding; ii) creeks’ network are enlarging ; iii) tidally influenced areas are rapidly encroaching;  v) river morphology is being changed. During the last three decades, it has been observed that the enormous water divergence of Indus river system in the upstream areas have tremendously depleted the water-flow and the sediment discharges to downstream areas particularly into the delta region resulting in the deterioration of deltaic environment, ecosystem, geomorphology and consequently causing the socioeconomic crises in the area. Study also found that overall delta degradation has severely affected the agriculture activities of the deltaic region, resulting in the decreasing in cultivated land, production and yield of the crops.